Lipid peroxidation and antioxidant status in blood of rheumatoid arthritis patients
نویسندگان
چکیده
منابع مشابه
Antioxidant status & lipid peroxidation in patients with rheumatoid arthritis.
BACKGROUND & OBJECTIVES Rheumatoid arthritis (RA) is a debilitating, chronic multisystem disease with an unknown etiology. Recent findings indicate that increased oxidative stress and/or defective antioxidant status contribute to the etiology of RA. The present study was undertaken to examine the oxidant and antioxidant systems in patients with RA and healthy controls. METHODS Twenty two pati...
متن کاملCirculating lipid peroxidation, plasma and erythrocyte antioxidant status in patients with rheumatoid arthritis.
The aim of the study was to investigate the levels of lipid peroxidation, and both plasma and erythrocyte antioxidant states in patients with rheumatoid arthritis. The population consisted of 60 subjects divided into two groups, 30 subjects had evidence of rheumatoid arthritis and age and sex matched healthy subjects were studied as controls. The level of plasma and erythrocyte thiobarbituric a...
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Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...
متن کاملAntioxidant gap and lipid peroxidation in patients with rheumatoid arthritis: Relationship to disease manifestations and activity
Citrullinated synovial antigens and the antibodies produced against them play a important role in the path physiology of RA[1]. Anti-CCP antibody positivity seems to be associated with increased synovial fluid oxidant activity (increased MDA and MPO levels) in patients with RA[2]. Excessive free radical production rather than impaired antioxidant enzymes activity due to autoantibody inhibition ...
متن کاملAntioxidant Status and Lipid Peroxides in Rheumatoid Arthritis
Oxygen free radicals have been implicated as mediators of tissue damage in patients with rheumatoid arthritis. The aim of our study was to assess the lipid peroxide products and antioxidant status in rheumatoid arthritis patients (RA). The study involved determination of two plasma lipid peroxide products, malondialdehyde (MDA) and conjugated dienes (CD), two plasma antioxidant vitamins (C and ...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2006
ISSN: 0970-1915,0974-0422
DOI: 10.1007/bf02913075